Chemotherapy induced nail changes

Chemotherapy-induced nail changes: an unsightly nuisance.

P.S. is a 53-year-old female patient with stage IIB breast cancer. In November 2000, she received Adriamycin (Pfizer Inc., New York, NY) and Cytoxan (Bristol-Myers Squibb, New York, NY), along with Herceptin (Genentech, Inc., South San Francisco, CA), as part of a clinical trial. In July 2002, the patient was found to have a left supraclavicular axillary recurrence. Because of this recurrence, ...

Nail changes after chemotherapy.

Nail Changes During Docetaxel Containing Combination Chemotherapy

Nail toxicity following systemic chemotherapy is common. Onychopathy during the period of neutropenia following chemotherapy may cause subungual abscesses and serious infection. Despite taxoid-related toxicity being increasingly reported since 2000, there are still phase II systemic chemotherapy studies using taxoid that have never mentioned nail changes. Recently, new criteria for the evaluati...

Nail changes secondary to docetaxel chemotherapy : a case report

INTRODUCTION Docetaxel is a chemotherapy agent used in the management of many neoplastic conditions. Various side effects are known. Nail changes are often under-recognised or attributed to other causes. CASE PRESENTATION We report the case of a 66 year old gentleman who received docetaxel chemotherapy for non-small cell lung cancer. He had nail changes as a complication of the treatment. C...

Taxane-induced nail changes: incidence, clinical presentation and outcome.

The clinical characteristics of nail changes in seven patients receiving taxane-containing chemotherapy are described. They include nail pigmentation, subungual hematoma, Beau's lines and onycholysis and subungual suppuration. The incidence of such changes (ranging from 0% to 44%) is reviewed from a Medline search of the literature.